Postdoctoral Positions
Please contact Professor Karin Hauser directly, if you are interested to work as a Postdoctoral Fellow in our group.
PhD Positions
PhD Position in Experimental Molecular Biophysics
Applications are invited for a PhD position in the research group of Professor Karin Hauser at the University of Konstanz. The project is dedicated to study protein folding dynamics by time-resolved infrared (IR) spectroscopy. In particular, a home-built IR spectrometer with a laser-excited temperature-jump will be used to monitor sub-millisecond structural dynamics. Focus of the project is the understanding of molecular mechanisms in the stabilization of protein structures. Model peptides with novel site-specific infrared probes will be applied to analyze structural dynamics on the basis of individual amino acids, thereby exploring backbone and side-chain dynamics separately
We are looking for a highly motivated student who has successfully completed a master in (bio)physics or chemistry. The ideal candidate should have experience in spectroscopic techniques or laser spectroscopy or optics. Interest in biophysical research and interdisciplinary work is expected. Further requirements are the ability to work independently and in a team, as well as good English language proficiency.
The position is integrated in the Collaborative Research Center 969 “Chemical and Biological Principles of Cellular Proteostasis” (A2) and immediately available.
Interested candidates should send their application (including motivation letter, CV, brief summary of master thesis, certificates) by e-mail to Karin.Hauser@uni-konstanz.de.
----
PhD Position in Biophysical Chemistry
Applications are invited for a PhD position in the research group of Professor Karin Hauser at the University of Konstanz. The project is dedicated to study molecular interaction mechanisms with infrared spectroscopy. We established an ATR-FTIR spectroscopic approach to study aggregation pathways of polyglutamine (polyQ) proteins by the controlled initiation of the aggregation process facilitating the structural characterization of intermediates in dependence of time. Expanded glutamine repeats are found in many neurodegenerative diseases, but molecular mechanisms leading to disease-related aggregates or preventing aggregation are not well understood. Focus of the project is the further development of the infrared spectroscopic approach and the analysis of molecular interactions between polyQ repeats and chaperones. PolyQ aggregation kinetics and pathways shall be analyzed in the presence of chaperones to get insights into molecular mechanisms of chaperone function.
We are looking for a highly motivated student who has successfully completed a master in (bio)chemistry, (bio)physics, life science or biology. The ideal candidate should have a strong interest in spectroscopy and biophysical research. Further requirements are the ability to work independently and in a team, as well as good English language proficiency.
The position is integrated in the Collaborative Research Center 969 “Chemical and Biological Principles of Cellular Proteostasis” (A2) and immediately available.
Interested candidates should send their application (including motivation letter, CV, brief summary of master thesis, certificates) by e-mail to Karin.Hauser@uni-konstanz.de.
Bachelor/Master Projects
Candidates interested in Bachelor or Master projects in the area of (bio)molecular spectroscopy are most welcome to get in touch anytime to discuss possible projects.
For more detailed information about the projects please contact Prof. Karin Hauser.
Student Projects
Students who are interested in getting to know our group and the field of molecular spectroscopy are at any time welcome to get in touch about a semester project.