Negative and Positive Confinement Effects in Chiral Separation Chromatography Monitored with Molecular-Scale Precision by In-Situ Electron Paramagnetic Resonance (EPR) Techniques

Martin Wessig, Martin Spitzbarth, Alexander Klaiber, Malte Drescher and Sebastian Polarz

Langmuir 2017, 33, 11968 - 11976.

Heavy-atom effect on optically excited triplet state kinetics

Christian Hintze, Tobias O. Morgen and Malte Drescher

PLoS ONE 2017, 12, 11, e0184239.

Simultaneous IR-spectroscopic observation of α-synuclein, lipids, and solvent reveals an alternative membrane-induced oligomerization pathway

Mohammad A. Fallah, Hanne R. Gerding, Christian Scheibe, Malte Drescher, Christiaan Karreman, Stefan Schildknecht, Marcel Leist and Karin Hauser

ChemBioChem 2017, 18, 2312 – 2316.

Time-, spectral- and spatially resolved EPR spectroscopy enables simultaneous monitoring of diffusion of different guest molecules in nano-pores

Martin Spitzbarth, Andreas Scherer, Andreas Schachtschneider, Peter Imming, Sebastian Polarz and Malte Drescher

 J. Magn. Reson. 2017, 283, 45 - 51.

Room-temperature in-cell EPR spectroscopy: Alpha-Synuclein disease variants remain intrinsically disordered in the cell

Julia Cattani, Vinod Subramaniam and Malte Drescher

Phys. Chem. Chem.Phys. 2017, 19, 18147 - 18151.

Recommended in F1000Prime as being of special significance in its field by F1000 Faculty Member Vladimir Uversky.

Electron Paramagnetic Resonance Spectroscopy

Sabrina Weickert and Malte Drescher

In: Z. Wang, U. Wille and E. Juaristi (eds), Encyclopedia of Physical Organic Chemistry, vol. 5. John Wiley & Sons, Inc., Hoboken, NJ, 2017, 2911 - 2956.

Molecular quantum spin network controlled by a single qubit

Lukas Schlipf, Thomas Oeckinghaus, Kebiau Xu, Durga Bhaktavatsala Rao Dasari, Andrea Zappe, Felipe Favaro de Oliveira, Bastian Kern, Mykhailo Azarkh, Malte Drescher, Markus Ternes, Klaus Kern, Joerg Wrachtup and Amit Finkler

Sci. Adv. 2017,  3, 8, e1701116.

Alpha-Synuclein disease mutations are structurally defective and locally affect membrane binding

Marta Robotta, Julia Cattani, Juliana Martins, Vinod Subramaniam and Malte Drescher

J. Am. Chem. Soc. 2017, 139, 4254 - 4257.

Delocalization of Coherent Triplet Excitons in Linear Rigid Rod Conjugated Oligomers

Christian Hintze, Patrick Korf, Frank Degen, Friederike Schütze, Stefan Mecking, Ulrich E. Steiner and Malte Drescher

J. Phys. Chem. Lett. 2017, 8, 690 - 695.

Synthesis and EPR-spectroscopic characterization of the perchlorotriarylmethyl tricarboxylic acid radical (PTMTC) and its 13C labelled analogue (13C-PTMTC)

Marwa Elewa, Nadica Maltar-Strmečki, Hendrik Metz, Mohamed M. Said, Hosam A. El Shihawy, Mohamed El-Sadek, Juliane Frank, Simon Drescher, Malte Drescher, Karsten Mäder, Dariush Hinderberger and Peter Imming

Phys. Chem. Chem. Phys. 2017, 19, 6688 - 6697.

Long-range distance constraints in bio-macromolecules by a combined approach of site-directed spin labeling and double electron-electron resonance (DEER) spectroscopy

Mykhailo Azarkh and Malte Drescher

In: Webb G. (eds), Modern Magnetic Resonance. Springer, Cham, 2016, 1 - 18.

Photoexcited Triplet State Kinetics Studied by Electron Paramagnetic Resonance Spectroscopy

Christian Hintze, Ulrich E. Steiner and Malte Drescher

ChemPhysChem 2016, 18, 6 - 16.

In Situ Monitoring of Diffusion of Guest Molecules in Porous Media Using Electron Paramagnetic Resonance Imaging

Martin Spitzbarth, Tobias Lemke and Malte Drescher

J. Vis. Exp. 2016, 115, e54335.

View the Video

Laser-Induced Magnetic Dipole Spectroscopy

Christian Hintze, Dennis Bücker, Silvia Domingo Köhler and Malte Drescher

J. Phys. Chem. Lett. 2016, 7, 2204 - 2209.

TrmBL2 from Pytococcus furiosus interacts both with double-stranded and single-stranded DNA

 Sebastian Wierer, Peter Daldrop, Misbha Ud Din Ahmad, Winfried Boos, Malte Drescher, Wolfram Welte and Ralf Seidel

PLoS ONE 2016, 11, e0156098.

Site-Directed Spin Labeling of Proteins In Vitro and In Cells

Patrick Roser, Moritz Schmidt, Malte Drescher and Daniel Summerer

Org. Biomol. Chem. 2016, 14, 5468 - 5476.

Redox-Active Tetrauthenium Macrocycles Built From Divinylphenylene-Bridged Diruthenium Complexes

Stefan Scheerer, Michael Linseis, Evelyn Wuttke, Sabrina Weickert, Malte Drescher, Oliver Tröppner, Ivana Ivanović-Burmazović, Andreas Irmler, Fabian Pauly and Rainer F. Winter

Chem. Eur. J. 2016, 22, 9574 - 9590.

Genetically Encoded Spin Labels for In Vitro and In-Cell EPR Studies of Native Proteins

Moritz Schmidt, Artem Fedoseev, Daniel Summerer and Malte Drescher

In: P Qin, K. Warncke (eds), Methods in Enzymology, vol 563: Electron Paramagnetic Resonance Investigations of Biological Systems by Using Spin Labels, Spin Probes, and Intrinsic Metal Ions, Part A. Academic Press, UK, 2015, 483 - 502.

Proteinvermessung: Präzise Abstandsverteilungen im Nanometerbereich

Julia Cattani, Marta Robotta and Malte Drescher

BIOspektrum 2015, 21, 718 - 720.

Probing of Chain Conformations in Conjugated Polymer Nanoparticles by Electron Spin Resonance Spectroscopy

Christian Hintze, Friederike Bettina Schütze, Malte Drescher and Stefan Mecking

Phys. Chem. Chem. Phys. 2015, 17, 32289 - 32296.

EPR Distance Measurements in Native Proteins with Genetically Encoded Spin Labels

Moritz J. Schmidt, Artem Fedoseev, Dennis Bücker, Julia Borbas, Christine Peter, Malte Drescher and Daniel Summerer

ACS Chem. Biol. 2015, 10, 2764 - 2771.

Pulsed EPR spectroscopy distance measurements of DNA internally labelled with Gd3+-DOTA

Filip Wojciechowski, Andreas Gross, Isabelle Holder, Laura Knörr, Malte Drescher and  Jörg S. Hartig

Chem. Commun. 2015, 51, 13850 - 13853.

Directional Materials - Nanoporous Organosilica Monoliths with Multiple Gradients Prepared Using Click Chemistry

Andreas Schachtschneider, Martin Wessig, Martin Spitzbarth, Adrian Donner, Christian Fischer, Malte Drescher and Sebastian Polarz

Angew. Chem. 2015, 127, 10611 - 10615.

Simultaneous Monitoring Macroscopic and Microscopic Diffusion of Guest Molecules in Silica and Organosilica Aerogels by Spatially and Time Resolved Electron Paramagnetic Resonance Spectroscopy

 Martin Spitzbarth, Martin Wessig, Tobias Lemke, Andreas Schachtschneider, Sebastian Polarz and Malte Drescher

J. Phys. Chem. C 2015, 119, 17474 - 17479.

Simultaneous Iterative Reconstruction Technique Software for Spectral-spatial EPR Imaging

Martin Spitzbarth and Malte Drescher

J. Magn. Reson. 2015, 257, 79 - 88.

Multiple scale investigation of molecular diffusion inside functionalized porous hosts using a combination of magnetic resonance methods

Martin Wessig, Martin Spitzbarth, Malte Drescher, Rainer Winter and Sebastian Polarz

Phys. Chem. Chem. Phys. 2015, 17, 15976 - 15988.

Sportbootführerschein See für Dummies

Malte Drescher

1. Auflage, Wiley-VCH, Weinheim, 2015

ISBN 978-3-527-70819-2

Alpha-Synuclein binds to the inner membrane of mitochondria in an alpha-helical conformation

Marta Robotta, Hanne R. Gerding, Antonia Vogel, Karin Hauser, Stefan Schildknecht, Christiaan Karreman, Marcel Leist, Vinod Subramaniam and Malte Drescher

ChemBioChem 2014, 15, 2499 - 2502.

Gd(III)-PyMTA label is suitable for in-cell EPR

Mian Qi, Andreas Gross, Gunnar Jeschke, Adelheid Godt and Malte Drescher

J. Am. Chem. Soc. 2014, 136, 15366 - 15378.

Genetisch kodierte, spinmarkierte künstliche Aminosäuren für Abstandsmessungen mittels ESR-Spektroskopie

Moritz Schmid, Daniel Summerer and Malte Drescher

Analytik News, 18.06.2014

Monitoring Enzymatic ATP Hydrolysis by EPR Spectroscopy

Stephan Hacker, Christian Hintze, Andreas Marx and Malte Drescher

Chem. Commun. 2014, 50, 7262 - 7264.

A bacterial DNA quadruplex with exceptional K+ selectivity and unique structural polymorphism

Charlotte Rehm, Isabelle Holder, Andreas Gross, Filip Wojciechowski, Maximilian Urban, Malte Sinn, Malte Drescher and Jörg S. Hartig

Chem. Sci. 2014, 5, 2809 - 2818.

A new Building Block for DNA Network Formation by Self-Assembly and Polymerase Chain Reaction

Holger Bußkamp, Sascha Keller, Marta Robotta, Malte Drescher and Andreas Marx

Beilstein J. Org. Chem. 2014, 10, 1037 - 1046.

A genetically encoded spin label for EPR distance measurements

Moritz J. Schmidt, Julia Borbas, Malte Drescher and Daniel Summerer

J. Am. Chem. Soc. 2014, 136, 1238 - 1241.

The NOX1/4 Inhibitor GKT136901 As Selective and Direct Scavenger of Peroxynitrite

Stefan Schildknecht, Annemarie Weber, Hanne R. Gerding, Regina Pape, Marta Robotta, Malte Drescher, Andreas Marquardt, Andreas Daiber, Boris Ferger and Marcel Leist

Curr. Med. Chem 2013, 21, 365 - 376.

Structural Characterization of Quadruplex DNA with in-cell EPR approaches

Isabelle T. Holder, Malte Drescher and Jörg S. Hartig

Bioorg. Med. Chem. 2013, 21, 6156 - 6161.

Oxidative and nitrative alpha synuclein modifications and proteostatic stress: implications for disease mechanisms and interventions in synucleinopathies

Stefan Schildknecht, Hanne R. Gerding, Christiaan Karreman, Malte Drescher, Hilal A. Lashuel, Tiago F. Outeiro, Donato A. Di Monte and Marcel Leist

J. Neurochem. 2013, 125, 491 - 511.

Triplet State Kinetics of Anthracene Studied by Pulsed Electron Paramagnetic Resonance

Silvia Domingo Köhler, Sebastian Höfel and Malte Drescher

Mol. Phys. 2013, 111, 2908 - 2913.

Probing Functional Group Specific Surface Interactions in Porous Solids Using ESR Spectroscopy as a Sensitive and Quantitative Tool

Martin Wessig, Malte Drescher and Sebastian Polarz

J. Phys. Chem. 2013, 117, 2805 - 2816.

Site-directed spin-labeling of nucleotides and the use of in-cell EPR to determine long-range distances in a biologically relevant environment

Mykhailo Azarkh, Vijay Singh, Oliver Okle, Isabelle T. Seemann, Daniel R. Dietrich, Jörg S. Hartig and Malte Drescher

Nat. Prot. 2013, 8, 131 - 147.

Intrazelluläre Elektronenspinresonanz-Spektroskopie

Malte Drescher

Nachr. Chem. 2012, 7, 718 - 721.

Elektronenspinresonanz-Spektroskopie 

Malte Drescher

Chem. Unserer Zeit 2012, 46, 129 - 195.

Abstand halten: Aufklärung multivalenter Bindungsmechanismen

Valentin Wittmann and Malte Drescher

Laborpraxis 2012, 36, 42 - 44.

EPR Spectroscopy - Applications in Chemistry and Biology

Malte Drescher and Gunnar Jeschke (eds)

EPR Spectroscopy. Topics in Current Chemistry, vol 321. Springer, Berlin, Heidelberg, 2012.

Top Curr. Chem 2012, 321.

Locally Resolved membrane binding affinity of the N-terminus of α-Synuclein

Marta Robotta, Christian Hintze, Stefan Schildknecht, Niels Zijlstra, Christian Jüngst, Christiaan Karreman, Martina Huber, Marcel Leist, Vinod Subramaniam and Malte Drescher

Biochemistry 2012, 51, 3960 - 3962.

Hunting the Chameleon: Structural Conformations of the Intrinsically Disordered Protein Alpha-Synuclein

Malte Drescher, Martina Huber and Vinod Subramaniam

ChemBioChem 2012, 13, 761 - 768.

Conformations of Individual Quadruplex Units studied in the Context of Extended Human Telomeric DNA 

Vijay Singh, Mykhailo Azarkh, Malte Drescher and Jörg S. Hartig

Chem. Commun. 2012, 48, 8258 - 8260.

Fully Delocalized (Ethynyl)(vinyl)phenylene Bridged Triruthenium Complexes in up to Five Different Oxidation States

Evelyn Wuttke, Florian Pevny, Yves-Marie Hervault, Lucie Norel, Malte Drescher, Rainer F. Winter and Stéphane Rigaut

Inorg. Chem. 2012, 51, 1902 - 1915.

Direct observation of non-Markovian radiation dynamics in 3D bulk photonic crystals 

Ulrich Hoeppe, Christian Wolff, Jens Küchenmeister, Jens Niegemann, Malte Drescher, Hartmut Benner and Kurt Busch

Phys. Rev. Lett. 2012, 108, 043603.

Intracellular Conformations of Human Telomeric Quadruplexes Studies by Electron Paramagnetic Resonance Spectroscopy 

Mykhailo Azarkh, Vijay Singh, Oliver Okle, Daniel R. Dietrich, Jörg S. Hartig and Malte Drescher

ChemPhysChem 2012, 13, 1444 - 1447.

Alpha-Synuclein: Horseshoe Conformation on Intact Large Unilamellar Vesicles

Marta Robotta, Patrick Braun, Bart van Rooijen, Vinod Subramaniam, Malte Drescher and Martina Huber

Biophys. J. 2011, 100, 184A.

EPR in Protein Science

Malte Drescher

In: M. Drescher, G. Jeschke (eds), EPR Spectroscopy. Topics in Current Chemistry, vol 321. Springer, Berlin, Heidelberg, 2012, 91 - 119.

Top. Curr. Chem. 2011, 321, 91 - 119.

Evaluation of spin labels for in-cell EPR by analysis of nitroxide reduction in cell extract of Xenopus laevis oocytes

Mykhailo Azarkh, Oliver Okle, Philipp Eyring, Daniel R. Dietrich and Malte Drescher

J. Magn. Reson. 2011, 212, 450 - 454.

Long-Range Distance Determination in a DNA Model System inside Xenopus Laevis Oocytes by In-Cell Spin-Label EPR

Mykhailo Azarkh, Oliver Okle, Vijay Singh, Isabelle T. Seemann, Jörg S. Hartig, Daniel R. Dietrich and Malte Drescher

ChemBioChem 2011, 12, 1992 - 1995.

Mechanism of Multivalent Carbohydrate-Protein Interactions Studied by EPR Spectroscopy

Patrick Braun, Bettina Nägele, Valentin Wittmann and Malte Drescher

Angew. Chem. 2011, 50, 8428 - 8431; selected as cover story.

Small molecule-triggered manipulation of DNA three-way-junctions 

Isabelle T.  Seemann, Vijay Singh, Mykhailo Azarkh, Malte Drescher and Jörg S. Hartig

J. Am. Chem. Soc. 2011, 133, 4706 - 4709.

Neuroprotection by minocycline due to direct and specific scavening of peroxynitrite

Stefan Schildknecht, Regina Pape, Nathalie Müller, Marta Robotta, Andreas Marquardt, Alexander Bürkle, Malte Drescher and Marcel Leist

J. Biol. Chem. 2011, 286, 4991 - 5002.

A short note on the analysis of distance measurements by electron paramagnetic resonance

Silvia Domingo Köhler, Martin Spitzbarth, Kay Diederichs, Thomas E. Exner and Malte Drescher

J. Magn. Reson. 2011, 208, 167 - 170.

Direct evidence of coexisting horseshoe and extended helix conformations of membrane bound alpha-Synuclein

Marta Robotta, Patrick Braun, Bart van Rooijen, Vinod Subramaniam, Martina Huber and Malte Drescher

ChemPhysChem 2011, 12, 267 - 269.

Fully delocalized (ethynyl)(vinyl)phenylene bridged diruthenium radical complexes

Florian Pevny, Emmanuel Di Piazza, Lucie Norel, Malte Drescher, Rainer F. Winter and Stéphane Rigaut

Organometallics 2010, 29, 5912 - 5918.

Organic Ligands Made Porous: Magnetic and Catalytic Properties of Transition Metals Coordinated to the Surfaces of Mesoporous Organosilica

Andreas Kuschel, Martin Luka, Martin Wessig, Malte Drescher, Mikhail Fonin, Gillian Kiliani and Sebastian Polarz

Adv. Funct. Mater. 2010, 20, 1133 - 1143.

Bifunctional mesoporous organosilica materials and their application in catalysis: Cooperative effects or not? 

Andreas Kuschel, Malte Drescher, Thomas Kuschel and Sebastian Polarz

Chem Mater. 2010, 22, 1472 - 1482.

The proline-rich domain of TonB possesses an extended polyproline II-like conformation of sufficient length to span the periplasm of Gram-negative bacteria

Silvia Domingo Köhler, Annemarie Weber, S. Peter Howard, Wolfram Welte and Malte Drescher

Protein Sci. 2010, 19, 625 - 630.

A stable lipid-induced aggregate of α-Synuclein

Malte Drescher, Bart van Rooijen, Gertjan Veldhuis, Vinod Subramaniam and Martina Huber

J. Am. Chem. Soc. 2010, 132, 4080 - 4082.

Structural characterization of ß-amyloid oligomer-aggregates by ion mobility mass spectrometry and electron spin resonance spectroscopy

Marius I. Iuraşcu, Claudia Cozma, Nick Tomczyk, John Rontree, Michael Desor, Malte Drescher and Michael Przybylski

Anal. Bioanal. Chem. 2009, 395, 2509 - 2519.

Human Telomeric Quadruplex Conformations studied by pulsed EPR

Vijay Singh, Mykhailo Azarkh, Thomas E. Exner, Jörg S. Hartig and Malte Drescher

Angew. Chem. Int. Ed. 2009, 48, 9728 - 9730.
and
Angew. Chem. 2009, 121, 9908 - 9910.

Monitoring Alzheimer amyloid peptide aggregation by EPR

Irina Sepkhanova, Malte Drescher, Nico J. Meeuwenoord, Roland W. Limpens, Roman I. Koning, Dmitri V. Filippov and Martina Huber

Appl. Magn. Reson. 2009, 36, 209 - 222.

Aggregation of Transmembrane Peptides Studied by Spin-Label EPR 

Francesco Scarpelli, Malte Drescher, Tania Rutters-Meijneke, Andrea Holt, Dirk Rijkers, J. Antoinette Killian and Martina Huber 

J. Phys. Chem. B 2009, 113, 12257 - 12264.

Spin-label EPR on a-Synuclein reveals differences in the membrane binding affinity of the two anti-parallel helices

Malte Drescher, Frans Godschalk, Gertjan Veldhuis, Bart van Rooijen, Vinod Subramaniam and Martina Huber

ChemBioChem 2008, 9, 2411 - 2416.

Antiparallel Arrangement of the Helices of Vesicle-Bound α-Synuclein 

Malte Drescher, Gertjan Veldhuis, Bart van Rooijen, Sergey Milikisyants, Vinod Subramaniam and Martina Huber

J. Am. Chem. Soc. 2008, 130, 7796 - 7797.

Proton irradiation defects in (fluoranthene)2PF6

Dominik Stöffler, Malte Drescher, David Saez de Jauregui, Jürgen Gmeiner and Elmar Dormann

Phys. Lett. A 2007, 363, 317 - 321.

Bilder der Leitungselektronen organischer Metalle

Malte Drescher

Fridericiana 2007, 67, 39.

Current density imaging by pulsed conduction electron spin resonance 

Malte Drescher, Noam Kaplan and Elmar Dormann

J. Magn. Reson. 2007, 184, 44 - 50.

3-d cylindrical X-band ESR imaging by a combined pulsed gradient Fourier and static gradient projection reconstruction method

Michael Glied, Malte Drescher and Elmar Dormann

J. Magn. Reson. 2006, 180, 163 - 169.

Conduction Electron Drift Velocity Measurement via ESR

Malte Drescher, Noam Kaplan, and Elmar Dormann

Phys. Rev. Lett. 2006, 96, 037601.

Featured in PRL Focus 2006, 17, 4.

Comparison of 2D ESR imaging techniques in two frequency ranges

Marco Ulrich, Tim Wokrina, Malte Drescher and Elmar Dormann

Appl. Magn. Reson. 2005, 29, 385 - 399.

Spatially Resolved and Integral Measurements of the Electron Spin Diffusion Properties of an Organic Quasi 1-D Conductor

Malte Drescher, David Saez de Jauregui, Stefan Matejcek and Elmar Dormann

Synth. Met. 2005, 152, 401 - 404.

Functional and Highly Spatially Resolved ESR Imaging

Malte Drescher

Aust. J. Chem. 2005, 58, 26 - 28. (invited)

Zebralike Patterned Organic Conductor with Periodic Modulation of Mobility and Peierls Transition

Malte Drescher, Noam Kaplan and Elmar Dormann

Phys. Rev. Lett. 2005, 94, 016404.

ESR imaging of pyrolytic carbon films 

Malte Drescher and Elmar Dormann

Europhys. Lett. 2004, 67, 847 - 853.

Chemical vapour infiltration of pyrolytic carbon – an electron spin resonance analysis

Malte Drescher, Moez Guellali, Klaus J. Hüttinger and Elmar Dormann

Synth. Met. 2003, 142, 13 - 19.

Pyrolytic carbon layers – an electron spin resonance analysis

Malte Drescher, Klaus J. Hüttinger and Elmar Dormann

Carbon 2003, 41, 773 - 783.