2022

  • Siu, H.-W., Hauser, K. "Observation of Oligomeric States Indicates a High Structural Flexibility Required for the Onset of PolyQ Fibrillization", J. Phys. Chem. Lett., 2022, 13, 4543-4548 [pdf]
  • Siu, H.-W.#, Stritt, P.#, Zhao, H., Hauser, K. "PolyQ aggregation studied by model peptides with intrinsic tryptophan fluorophores", Biophysical Chemistry, 2022, 284, 106782 [pdf]

2021

  • King, M., Avaro, J.T., Peter, C., Hauser, K., Gebauer, D. "Solvent-mediated isotope effects strongly influence the early stages of calcium carbonate formation: exploring D2O vs. H2O in a combined computational and experimental approach", Faraday Discussions, 2021, accepted DOI: 10.1039/D1FD00078K [pdf]
  • Scheibe, C., Karreman, C., Schildknecht, S., Leist, M., Hauser, K. "Synuclein family members prevent membrane damage by counteracting α-synuclein aggregation", Biomolecules, 2021, 11, 1067 [pdf]
  • Siu, H.-W., Heck, B., Kovermann, M., Hauser, K. "Template-assisted design of monomeric polyQ models to unravel the unique role of glutamine side chains in disease-related aggregation", Chem. Sci., 2021, 12, 412–426 [pdf]

2020

  • Krüger, A., Bürkle, A., Hauser, K.*, Mangerich, A.* "Real-time monitoring of PARP1-dependent PARylation by ATR-FTIR spectroscopy", Nat. Commun 2020, 11, 2174 [pdf]  
    uni press release (German) / (English)
  • Avaro, J.T., Wolf, S.L.P. , Hauser, K.*, Gebauer, D.* "Stable Prenucleation Calcium Carbonate Clusters Define Liquid‐Liquid Phase Separation", Angew. Chem. Int. Ed. 2020, 59, 6155 –6159 [pdf]  
    German Edition: Angew. Chem. 2020, 132, 6212 –6217  [pdf
  • Hinze, W.G., Fallah, M.A., Hauser, K. "Protein adsorption on ZnO films studied by ATR-FTIR spectroscopy",  Biomed. Spectros. and Imaging, 2020, 9, 47-54 [pdf]
  • Scheerer, D., Chi, H., McElheny, D., Keiderling, T., Hauser, K. "Enhanced sensitivity to local dynamics in peptides by use of temperature-jump IR-spectroscopy and isotope labeling", Biophys. J. Suppl., 2020, 118, 197a
  • Stritt, P., Jawurek, M., Hauser, K. "Application of tunable quantum cascade lasers to monitor dynamics of bacteriorhodopsin in the mid-IR spectral range", Biomed. Spectros. and Imaging, 2020, 9, 55-61 [pdf]
  • Scheerer, D., Chi, H., McElheny, D., Keiderling, T., Hauser, K. "Enhanced sensitivity to local dynamics in peptides by use of temperature-jump IR-spectroscopy and isotope labeling", Chem Eur J, 2020, 26, 3524-3534 [pdf ]

2019

  • Fallah, M.A., Hauser, K. "Immobilization approaches can affect protein dynamics: a surface-enhanced infrared spectroscopic study on lipid-protein interactions", Biomaterials Science , 2019, 7, 3204-3212 [pdf]
  • Krüger, A., Stier, A.,  Fischbach, A.,  Bürkle, A., Hauser, K., Mangerich, A. "Interactions of p53 with poly(ADP-ribose) and DNA induce distinct changes in protein structure as revealed by ATR-FTIR spectroscopy", Nucleic Acids Research , 2019, 47, 4843–4858 [pdf] 
    uni press release (German) (English)
  • Avaro, J., Ruiz-Agudo, C., Landwehr, E., Hauser, K., Gebauer, D. "Impurity-free amorphous calcium carbonate, a preferential material for pharmaceutic and medical applications", Eur. J. Mineral., 2019, 31, 231-236 [pdf]
  • Siu, H.-W., Heck, B., Kovermann, M., Hauser, K. " Design of polyQ peptides to study the dynamics of glutamine interactions spectroscopically", Eur Biophys J, 2019, 48, Suppl 1, S119 [pdf]
  • Jawurek, M., Stritt, P., Hauser, K. " Time-resolved infrared spectroscopy to analyze dynamic interactions of photoreceptors with biomimetic membranes", Eur Biophys J, 2019, 48, Suppl 1, S241 [pdf]
  • Scheerer, D., Chi, H., McElheny, D., Keiderling, T., Hauser, K. " Study of ß-sheet dynamics using isotope-induced frequency shifts of vibrationally coupled modes", Eur Biophys J, 2019, 48, Suppl 1, S119 [pdf]
  • Keiderling, T.A., Chi, H., McElheny, D., Scheerer, D.,  Islam, M.S., Hauser, K. "Isotopically edited vibrational spectra and dynamics for three-stranded ß-sheet peptides. DFT spectral and MD simulations", Biophys. J. 2019, 116, 17a–18a [pdf]

2018

  • Scheerer, D., Chi, H., McElheny, D., Keiderling, T.A., Hauser, K. "Isotopically site-selected dynamics of a three-stranded ß-sheet peptide detected with temperature-jump IR-spectroscopy", J. Phys. Chem. B, 2018, 122, 10445-10454 [pdf]
  • Jawurek, M., Dröden, J., Peter, B., Glaubitz, C., Hauser,K. "Lipid-induced dynamics of photoreceptors monitored by time-resolved step-scan FTIR spectroscopy", Chem.Phys., 2018, 512, 53-61 [pdf]
  • Yushchenko, T., Deuerling, E., Hauser, K. "Insights into the aggregation mechanism of polyQ proteins with different glutamine repeat lengths", Biophys. J., 2018, 114, 1847-1857 [pdf]
  • Scheibe, C., Hauser, K. "Orientation of lipids in solid supported lipid bilayers studied by polarized ATR-FTIR Spectroscopy", Biomed. Spectros. and Imaging, 2018, 7, 17-24 [pdf]
  • Krüger, A., Bürkle, A., Mangerich, A., Hauser, K. "A combined approach of surface passivation and specific immobilization to study biomolecules by ATR-FTIR spectroscopy", Biomed. Spectros. and Imaging, 2018, 7, 25-33 [pdf]
  • Keiderling, T.A., Chi, H., McElheny, D., Scheerer, D., Samer, S., Hauser, K., Vazquez, F. "Spectra and simulation of model ß-sheets and hairpins. Impact of turn and aromatic contacts on equilibria and dynamcis" Biophys. J. Suppl., 2018, 114, 53a pdf
  • Scheerer, D., Chi, H., McElheny, D., Samer, A., Keiderling, T.A., Hauser, K. "The Role of Aromatic Cross-links in Structure and Dynamics of Model Three-Stranded ß-sheet Peptides" , J.Phys.Chem. A, 2018, 122, 543–553 pdf
  • Fischbach, A.,  Krüger, A., Hampp, S., Assmann, G., Rank, L., Hufnagel, M., Stöckl, M., Fischer, J.M.F., Veith, S.,  Rossatti, P., Ganz, M., Ferrando-May, E.,  Hartwig, A., Hauser, K., Wiesmüller, L., Bürkle, A., Mangerich, A. "The C-terminal domain of p53 orchestrates the interplay between non-covalent and covalent poly(ADP-ribosyl)ation of p53 by PARP1", Nucleic Acids Research, 2018, 46, 804–822  pdf

2017

  • Fallah, M.A., Gerding, H.R., Scheibe, C., Drescher, M. Karreman, C., Schildknecht, S.,  Leist, M., Hauser, K. "Simultaneous IR-spectroscopic observation of α-synuclein, lipids, and solvent reveals an alternative membrane-induced oligomerization pathway", ChemBioChem, 2017, 18, 2312 – 2316 pdf
  • Popp, A.#, Scheerer, D.#, Heck, B., Hauser, K. "Biomolecular dynamics studied with IR-spectroscopy using quantum cascade lasers combined with nanosecond perturbation techniques", Spectrochim Acta A Mol Biomol Spectrosc, 2017, 181, 192–199 PDF
  • Keiderling, T.A., Chi, H., McElheny, D., Walker, A., Scheerer, D., Hauser, K. "Three-Strand β-Sheet Peptide Models. IR, VCD and ECD Spectra, T-Jump Dynamics and NMR Structures Support MD and DFT Simulatations" Biophys. J. Suppl., 2017, 112, 195a  PDF

2016

  • Henke, K., Welte, W., Hauser, K. "Direct monitoring of β-sheet formation in the outer membrane protein TtoA assisted by TtOmp85" Biochemistry, 2016, 55, 4333–4343
    Editors' Pick in World Biomedical Frontiers because of its innovation and potential for significant impact PDF
  • Fallah, M.A.#, Stanglmair, C.#, Pacholski, C., Hauser, K. "Devising self-assembled-monolayers for surface-enhanced infrared spectroscopy of pH-driven poly-L-lysine conformational changes" Langmuir, 2016, 32, 7356–7364 PDF
  • Jawurek, M., Glaubitz, C., Hauser, K. "Impact of the lipid environment on the protonation dynamics of bacteriorhodopsin studied with time-resolved step-scan FTIR spectroscopy" Biomed. Spectros. and Imaging, 2016, 5, 167-174 PDF
  • Popp, A., Scheerer, D., Chi, H., Keiderling, T.A., Hauser, K. "Site-specific dynamics of β-sheet peptides with DPro-Gly turns probed by laser-excited temperature-jump infrared spectroscopy" ChemPhysChem, 2016, 17, 1273-1280 PDF

2015

  • Farhadi Khouzani, M., Chevrier, D.M., Güttlein, P., Hauser, K., Zhang, P., Hedin, N., Gebauer, D. "Disordered amorphous calcium carbonate from direct precipitation" CrystEngComm, 2015, 17, 4842-4849 PDF
  • Yushchenko, T., Schloemer, R., Deuerling, E., Hauser, K. "Molecular processes of polyQ protein aggregation studied with time-resolved ATR-FTIR spectroscopy" Eur. Biophys. J. Suppl.1, 2015, 44, 159 PDF
  • Henke, K. Odermatt, M., Welte, W., Hauser, K. "Infrared spectroscopic folding studies of outer membrane proteins" Eur. Biophys. J. Suppl.1, 2015, 44, 155 PDF
  • Donten, M.L., Hassan, S., Popp, A., Halter, J., Hauser, K., Hamm, P. "pH-jump induced leucine zipper folding beyond the di ffusion limit" J. Phys. Chem. B, 2015, 119, 1425–1432 PDF

2014

  • Popp, A., Wu, L., Keiderling, T.A., Hauser, K. "Effect of Hydrophobic Interactions on the Folding Mechanism of β-hairpins" J. Phys. Chem. B, 2014, 118, 14234–14242  PDF
  • Robotta, M., Gerding, H.R., Vogel, A., Hauser, K., Schildknecht, S. Karreman, C., Leist, M, Subramaniam, V., Drescher, M. "Alpha-Synuclein binds to the inner membrane of mitochondria in an alpha-helical conformation“ ChemBioChem, 2014, 15, 2499-2502 PDF
  • Henke, K., Odermatt, M., Welte, W., Hauser, K. "Stability of the Thermus thermophilus outer membrane protein TtoA against heat and denaturants" Biomed. Spectrosc. and Imaging, 2014, 3, 51-56 PDF
  • Popp, A., Wu, L., Keiderling, T.A., Hauser, K. "Time-resolved temperature-jump IR-measurements on ß-hairpin peptides with alternate cross-strand interactions" Biophys. J. Suppl., 2014, 106, 52a PDF 
  • Heck, B.S., Doll, F., Hauser, K. "Length-dependent conformational transitions of polyglutamine repeats as molecular origin of fibril initiation" Biophys. Chem., 2014, 185, 47–57 PDF
  • Deeg, A.A., Rampp, M.S., Popp, A., Pilles, B.M., Schrader, T. E., Moroder, L., Hauser, K., Zinth, W. "Isomerization and Temperature Jump Induced Dynamics of a Photo-Switchable ß-Hairpin" Chem. Eur. J., 2014, 20, 694-703 PDF

2013

  • Heck, B.S., Doll, F., Popp, A., Hauser, K. "Fibril formation of polyglutamine repeats: a spectroscopic study" Eur. Biophys. J. Suppl.1, 2013, 42, 62 PDF
  • Hauser, K. "Infrared-spectroscopy of protein folding, misfolding and aggregation" in: Encyclopedia of Biophysics, G.C.K. Roberts (ed.), ISBN: 978-3-642-16711-9, Springer Berlin-Heidelberg, 2013, vol.2, 1089-1095 PDF

2012

  • Popp, A., Wu, L. Keiderling, T.A., Hauser, K. "Impact of beta-turn sequence on beta-hairpin dynamics studied with infrared detected temperature jump" Spectroscopy, 2012, 27, 557-564 PDF
  • Hauser, K. "Dynamics of alpha-helix and beta-sheet formation studied by laser-induced temperature-jump IR-spectroscopy" book chapter in: "Protein Folding and Misfolding - Shining Light by Infrared Spectroscopy", D. Naumann and H. Fabian (eds.), ISBN 978-3-642-22229-0 , Springer Berlin-Heidelberg, 2012, 147-170 PDF

2011

  • Krejtschi, C., Hauser, K. "Stability and Folding Dynamics of Polyglutamic Acid" Eur. Biophys. J., 2011, 40, 673-685 PDF
  • Krejtschi, C., Hauser, K. "Folding rates studied by a combination of static and time-resolved infrared spectroscopy" Eur. Biophys. J. Suppl.1, 2011, 40, 208 PDF

2010

  • Hauser, K., Ridderbusch, O., Roy, A., Hellerbach, A., Huang, R., Keiderling, T.A. "Comparison of isotopic substitution methods for equilibrium and T-jump infrared studies of beta-hairpin peptide conformation" J. Phys. Chem. B, 2010, 114, 11628-11637 PDF
  • Kopitz, A., Soppa, J., Hauser, K. "Analysis of a Hybrid TATA Box Binding Protein Originating from Mesophilic and Thermophilic Donor Organisms" Spectroscopy, 2010, 24, 233-237 PDF

2009

  • Weidemüller, C., Hauser, K. "Ion transport and energy transduction of P-type ATPases: implications from electrostatic calculations" Biochim. Biophys. Acta - Bioenergetics, 2009, 1787, 721-729 PDF
  • Kopitz, A., Soppa, J., Krejtschi, C., Hauser, K. "Differential stability of two TBP proteins from archaea with different optimal growth temperatures" Spectrochim Acta A Mol Biomol Spectrosc, 2009, 73, 799-804 PDF
  • Krejtschi, C., Ridderbusch, O., Huang, R., Wu, L., Keiderling, T. A., Hauser, K. "Folding dynamics of peptides studied by time-resolved infrared spectroscopy" Eur. Biophys. J. Suppl. 1, 2009, 38, 209 PDF
  • Weidemüller, C., Siu, S., Böckmann, R., Hauser, K. "Ion transport and energy transduction of P-type ATPases studied by simulations " Eur. Biophys. J. Suppl. 1, 2009, 38, 59 PDF
  • Krejtschi, C., Wu, L., Huang, R., Hauser, K., Keiderling, T. A. "Site-specific folding dynamics of isotopically labeled peptides studied by time-resolved infrared-spectroscopy" Biophys. J. Suppl., 2009, 96, 73a PDF

2008

  • Weidemüller, C., Hauser, K.: "A computational approach to study the energy transduction  mechanism in the Na+/K+-ATPase" in: "From Computational Biophysics to System Biology (CBSB08)", U.H.E. Hansmann, J. Meinke, S. Mohanty, W. Nadler, O. Zimmermann (eds.), ISBN 978-3-9810843-6-8, NIC Series, Jülich 2008, 40, 409-411 PDF
  • Weidemüller, C., Hauser, K. "Impact of an electric field on P-type ATPases" Spectroscopy, 2008 22, 319-325 PDF
  • Krejtschi, C., Huang, R., Keiderling, T.A., Hauser, K. "Time-resolved temperature-jump infrared spectroscopy of peptides with well-defined secondary structure: a trpzip beta-hairpin variant as an example" Vibrational Spectroscopy, 2008, 48, 1-7 PDF
  • Hauser, K., Krejtschi, C., Huang, R., Wu, L., Keiderling, T.A. "Site-specific relaxation kinetics of a tryptophan zipper hairpin peptide using temperature-jump IR-spectroscopy and isotopic labeling" J. Am. Chem. Soc., 2008, 130, 2984-2992 PDF
  • Huang, R., Krejtschi, C., Hauser, K., Keiderling, T.A. "TrpZip-based beta hairpin equilibrium and temperature jump IR studies enhanced by site-specific isotope labeling" Biophys. J. Suppl., 2008, 611 PDF
  • Andersson, J., Hauser, K., Karjalainen, E.-L., Barth, A. "Protonation and hydrogen bonding of Ca2+ site residues in the E2P phosphoenzyme intermediate of sarcoplasmic reticulum Ca2+-ATPase studied by a combination of infrared experiments and electrostatic calculations" Biophys. J., 2008, 94, 600-611 PDF

2007

  • Hauser, K., Barth, A. "Side-chain protonation and mobility in the sarcoplasmic reticulum Ca2+-ATPase: implications for proton countertransport and Ca2+release" Biophys. J., 2007, 93, 1-12 PDF
  • Karjalainen, E.-L., Hauser, K., Barth, A. "Proton paths in the sarcoplasmic Ca2+-ATPase" Biochim. Biophys. Acta - Bioenergetics, 2007, 1767, 1310-1318 PDF
  • Huang, R., Krejtschi, C, Hauser, K., Kim, J., Keiderling, T.A. "Thermal unfolding of a beta hairpin studied with IR spectra enhanced by site-specific isotope labeling" Biophys. J. Suppl., 2007, 92, 208a 

2006

  • Hauser, K. "Electrostatic calculations for assignment of IR difference bands to carboxyl groups getting protonated during protein reactions" Biopolymers, 2006, 82, 430-434 PDF
  • Sukumaran, S., Hauser, K., Maier, E., Benz, R., Mäntele, W. "Tracking the unfolding and refolding pathways of outer membrane protein porin from Paracoccus denitrificans" Biochemistry, 2006, 45, 3972-3980 PDF
  • Sukumaran, S., Hauser, K., Maier, E., Benz, R., Mäntele, W. "Structure-function correlation of outer membrane protein porin from Paracoccus denitrificans" Biopolymers, 2006, 82, 344-348 PDF

2005

  • Sukumaran, S., Hauser, K., Rauscher, A., Mäntele, W. "Thermal stability of outer membrane protein porin from Paracoccus denitrificans: FT-IR as a spectroscopic tool to study lipid-protein interaction" FEBS Letters, 2005, 579, 2546-2550 PDF
  • Andersson, J., Hauser, K., Barth, A. "Protonation of Ca2+-ATPase residues upon Ca2+ release" Journal of General Physiology, 2005, 126 (1), 15A-16A, 35 PDF
  • Hauser, K. "Simulation von Enzymzuständen am Computer - ein Weg zum Verständnis molekularer Details"; G.I.T. Labor Fachzeitschrift, 10/2005, GIT Verlag (Wiley Company) PDF

2004

  • Hauser, K., Mao, J., Gunner, M. "PH dependence of heme electrochemistry in cytochromes investigated by multiconformation continuum electrostatic calculations" Biopolymers, 2004, 74, 51-54 PDF

2003

  • Mao, J., Hauser, K., Gunner, M. "How cytochromes with different folds control heme redox potentials" Biochemistry,2003, 42, 9829-9840 PDF
  • Gunner, M., Mao, J., Hauser, K., Kim, J. "Adding conformational flexibility to continuum electrostatics: Assaying the stability and importance of charges buried in proteins." J. Am Chem Soc., 2003, 225: 116-COMP Part1
  • Hauser, K., Mao, J., Gunner, M. "PH dependence of heme electrochemistry in cytochromes investigated by multiconformation continuum electrostatic calculations" in:"Spectroscopy of Biological Molecules", ISBN 963 482 614 8, B. Szalontai & Z. Kota (eds.), Szeged 2003, 185

2002

  • Hauser, K., Engelhard, M., Riesle, J., Oesterhelt, D., Friedman, N., Sheves, M., Siebert, F. "Interpretation of amide I difference bands observed during protein reactions using site-directed isotopically labeled bacteriorhodopsin as a model system" J. Phys. Chem. A, 2002, 106, 3553-3559 PDF
  • Siebert F., Hauser K., Engelhard M., Sheves M., Oesterhelt D. "Interpretation of amide I difference bands observed during protein reactions using site-directed isotopically labeled bacteriorhodopsin as a model system" Biophys. J. Suppl., 2002, 82, 37a-38a PDF

1997

  • Georg, H., Hauser, K., Rödig, C., Weidlich, O., Siebert, F. "Time-resolved infrared spectroscopy of biomolecules" book chapter in: "Biomolecular Structures and Dynamics", G. Vergoten & T. Theophanides (eds.), ISBN 0-7923-2773X, NATO ASI Series E, 342, 1997, 243-261
  • Hauser, K., Engelhard, M., Siebert, F. "Localisation of structural changes of the alpha-helices during the photoreaction of bacteriorhodopsin by FTIR-difference-spectroscopy of site-directed isotope labelled T46C-BR-mutants" in: "Spectroscopy of Biological Molecules: Modern Trends", P. Carmona, R. Navarro and A. Hernanz (eds.), Kluwer Academic Publishers, Dordrecht, 1997, 111-112

1995

  • Barth, A., Hauser, K., Mäntele, W., Corrie, J. E. T., Trentham, D. R. "Photochemical release of ATP from "caged ATP" studied by time-resolved infrared spectroscopy" J. Am. Chem. Soc., 1995, 117, 10311-10316 PDF