D. Kläge, E. Müller, J.S. Hartig
A comparative survey of the influence of small self-cleaving ribozymes on gene expression in human cell culture
RNA Biology, 2023, 23,1
doi: 10.1080/15476286.2023.2296203
D. Funck, M. Sinn, G. Forlani, J.S. Hartig
Guanidine Production by Plant Homoarginine-6-hydroxylases
eLife, 2023, 12:RP91458
doi: 10.7554/eLife.91458.1
B. Silkenath, D. Kläge, H. Altwein, N. Schmidhäuser, G. Mayer, J. S. Hartig, V. Wittmann
Phosphonate and Thiasugar Analogues of Glucosamine-6-phosphate: Activation of the glmS Riboswitch and Antibiotic Activity
ACS Chem. Biol. 2023, 18
doi: 10.1021/acschembio.3c00452
J. R. Fleming, F. Hauth, J. S. Hartig and O. Mayans
Crystal structure of a GCN5-related N-acetyltransferase from Lactobacillus curiae
Acta Crystallographica, 2023, 79(8), 217-223
doi: 10.1107/S2053230X2300571X
F. Hauth, D. Funck and J. S. Hartig
A standalone editing protein deacylates mischarged canavanyl-tRNAArg to prevent canavanine incorporation into proteins
Nucleic Acids Research, 2023, 51(5), 2001-2010
doi: 10.1093/nar/gkac1197
F. Lenkeit, I. Eckert, M. Sinn, F. Hauth, J. S. Hartig* and Z. Weinberg*
A variant of guanidine-IV riboswitches exhibits evidence of a distinct ligand specificity
RNA Biology, 2023, 20, 10
doi: 10.1080/15476286.2022.2160562
M. Sinn, M. Stanoppi, F. Hauth, J. R. Fleming, D. Funck, O. Mayans, and J. S. Hartig
Guanidino acid hydrolysis by the human enzyme annotated as agmatinase
Scientific Reports, 2022, 12, 22088
doi: 10.1038/s41598-022-26655-4
F. Hauth, H. Buck, M. Stanoppi and J. S. Hartig
Canavanine utilization via homoserine and hydroxyguanidine by a PLP-dependent gamma-lyase in Pseudomonadaceae and Rhizobiales
RSC Chemical Biology, 2022, 3,1240-1250
doi: 10.1039/d2cb00128d
D. Funck, M. Sinn, J. Fleming, M. Stanoppi, J. Dietrich, R. López-Igual, O. Mayans, and J. S. Hartig
Discovery of a Ni2+-dependent guanidine hydrolase in bacteria
Nature, 2022, 603,0515-521
doi: 10.1038/s41586-022-04490-x
F. Hauth, H. Buck, and J. S. Hartig
Pseudomonas canavaninivorans sp. nov. isolated from bean rhizosphere
International Journal of Systematic and Evolutionary Microbiology, 2022, 72(1)
doi: 10.1099/ijsem.0.005203
J. Steuer, O. Kukharenko, K. Riedmiller, J. S. Hartig, and C. Peter
Guanidine-II Aptamer Conformations and Ligand Binding Modes through the Lens of Molecular Simulation
Nucleic Acids Research, 2021, 49, 7954-7965
doi. 10.1093/nar/gkab592
M. Finke, D. Brecht, J. Stifel, K. Gense, M. Gamerdinger, and J. S. Hartig
Efficient splicing-based RNA regulators for tetracycline-inducible gene expression in human cell culture and C. elegans
Nucleic Acids Research, 2021, 49, e71
doi: 1093/nar/gkab233
M. Sinn, F. Hauth, F. Lenkeit, Z. Weinberg, and J. S. Hartig
Widespread bacterial utilization of guanidine as nitrogen source
Molecular Microbiology, 2021, 116(1), 200-210
doi: 10.1111/mmi.14702
F. Lenkeit, I. Eckert, J. S. Hartig, and Z. Weinberg
Discovery and Characterization of a Fourth Class of Guanidine Riboswitches
Nucleic Acids Research, 2020, 16, 12889-12899
doi: 10.1093/nar/gkaa1102
M. Spöring, R. Boneberg, and J. S. Hartig
Aptamer-mediated control of polyadenylation for gene expression regulation in mammalian cells
ACS Synthetic Biology, 2020, 9, 3008-3018
doi: 10.1021/acssynbio.0c00222
Q. Qi, C. Wang, W. Li, J. Dang, M. Hao, S. Lv, X. Dong, Y. Gu, P. Wu, W. Zhang, Y. Chen, and J. S. Hartig
A Cu(II)-ATP complex efficiently catalyzes enantioselective Diels-Alder reactions
Nature Communications, 2020, 11, 4792
doi: 10.1038/s41467-020-18554-x
B. Strobel, M. J. Düchs, D. Blazevic, P. Rechtsteiner, C. Braun, K.S. Baum-Kroker, B. Schmid, T. Ciossek, D. Gottschling, J. S. Hartig, and S. Kreuz,
A Small-Molecule-Responsive Riboswitch Enables Conditional Induction of Viral Vector-Mediated Gene Expression in Mice
ACS Synthetic Biology, 2020, 9, 1292-1305
doi: 10.1021/acssynbio.9b00410
B. Strobel, M. Spöring, H. Klein, S. Sayols Puig, J. S. Hartig, and S. Kreuz,
High-throughput identification of synthetic riboswitches by barcode-free amplicon-sequencing in human cells
Nature Communications, 2020, 11, 714
doi: 10.1038/s41467-020-14491-x
C. Wang, M. Hao, Q. Qi, Y. Chen, J. S. Hartig
Chemical synthesis, purification, and characterization of 3´-5´-linked canonical cyclic dinucleotides (CDNs)
Methods in Enzymology, 2019, 625, 41-59
doi: 10.1016/bs.mie.2019.04.022
C. Wang, M. Hao, Q. Qi, J. Dang, X. Dong, S. Lv, L. Xiong, H. Gao, G. Jia, Y. Chen, J. S. Hartig, and C. Li
Highly Efficient Cyclic Dinucleotide-Based Artificial Metalloribozymes for Enantioselective Friedel-Crafts Reactions in Water
Angewandte Chemie International Edition, 2019, 59(9), 3444-3449
doi.org/10.1002/anie.201912962
M. Spöring, M. Finke, and J. S. Hartig
Aptamers in RNA-based switches of gene expression
Current Opinion in Biotechnology, 2019, 63, 34-40
doi: 10.1016/j.copbio.2019.11.008
N. Shanidze, F. Lenkeit, J. S. Hartig, and D. Funck
A theophylline-responsive riboswitch regulates expression of nuclear-encoded genes in Arabidopsis
Plant Physiology, 2019, 182,123-135
doi: 10.1104/pp.19.00625
J. Stifel and J. S. Hartig
Ribozymes for controlling gene expression (book chapter)
Ribozymes, Wiley-VCH, 2019, in press
doi: 10.1002/9783527814527.ch19
L. Wurmthaler, M. Sack, K. Gense, J. S. Hartig, and M. Gamerdinger
A tetracycline-dependent ribozyme switch allows conditional induction of gene expression in Caenorhabditis elegans
Nature Communications, 2019, 10, 491
doi: 10.1038/s41467-019-08412-w
M. Sack, J. Stifel, S. G. Kreft, E. Deuerling, and J. S. Hartig
Neomycin-dependent Hammerhead Ribozymes for the Direct Control of Gene Expression in Saccharomyces cerevisiae
Methods, 2019, 161, 35-40
doi: 10.1016/j.ymeth.2019.01.004
J. Stifel, M. Spöring, and J. S. Hartig
Expanding the toolbox of synthetic riboswitches with guanine-dependent aptazymes
Synthetic Biology, 2019, 4, ysy022
doi: 10.1093/synbio/ysy022
S. Knorr, M. Sinn, D. Galetskiy, R. M. Williams, C. Wang, N. Müller, O. Mayans, D. Schleheck, and J. S. Hartig
Widespread bacterial lysine degradation proceeding via glutarate and L-2-hydroxyglutarate
Nature Communications, 2018, 9, 5071
doi: 10.1038/s41467-018-07563-6
J. S. Hartig
Aptamer-Based Control of Gene Expression Utilizing Endogenous miRNAs (Commentary)
Molecular Therapy, 2018, 26, 5, 1178-1180
doi: 10.1016/j.ymthe.2018.04.010
L. A. Wurmthaler, B. Klauser, and J. S. Hartig
Highly motif- and organism-dependent effects of naturally occurring hammerhead ribozyme sequences on gene expression
RNA Biology, 2018, 15, 231-241
doi: 10.1080/15476286.2017.1397870
C. Wang, M. Sinn, J. Stifel, A. C. Heiler, A. Sommershof, and J. S. Hartig
Synthesis of All Possible Canonical (3´-5´-Linked) Cyclic Dinucleotides and Evaluation of Riboswitch Interactions and Immune-Stimulatory Effects
Journal of the American Chemical Society, 2017, 139, 16154-16160
doi: 10.1021/jacs.7b06141
E. Aghdam Mehdizadeh, M. Sinn, V. Tarhriz, A. Barzegar, J. S. Hartig, M. S. Hejazi
TPP riboswitch characterization in Alishewanella tabrizica and Alishewanella aestuarii and comparison with other TPP riboswitches
Microbiology Research, 2017, 195, 71-80
doi: 10.1016/j.micres.2016.11.003
M. Felletti, A. Bieber, and J. S. Hartig
The 3'-untranslated region of mRNAs as a site for ribozyme cleavage-dependent processing and control in bacteria
RNA Biology, 2016, 14. 1522-1533
doi: 10.1080/15476286.2016.1240141
M. Felletti and J. S. Hartig
Ligand-dependent Ribozymes (Review)
WIREs RNA, 2016, DOI: 10.1002/wrna.1395
doi: 10.1002/wrna.1395
M. Felletti, J. Stifel, L. A. Wurmthaler, S. Geiger, J. S. Hartig
Twister ribozymes as highly versatile expression platforms for artificial riboswitches
Nature Communications, 2016, 12834
doi: 10.1038/ncomms12834
M. J. Urban, I. T. Holder, M. Schmid, V. Fernandez Espin, J. Garcia de la Torre, J. S. Hartig, H. Cölfen
Shape Analysis of DNA-Au-Hybrid Particles by Analytical Ultracentrifugation
ACS Nano, 2016, 10, 7418-7427
doi: 10.1021/acsnano.6b01377
M. Voges, C. Schneider, M. Sinn, J. S. Hartig, R. Reimer, J. Hauber, K. Moelling
Abolishing HIV-1 infectivity using a polypurine tract-specific G-quadruplex-forming oligonucleotide
BMC Infectious Diseases, 2016, 16,358
doi: 10.1186/s12879-016-1713-x
M. Felletti, B. Klauser, and J. S. Hartig
Screening of Genetic Switches Based on the Twister Ribozyme Motif
Methods in Molecular Biology, 2016, 1380, 225-239
doi: 10.1007/978-1-4939-3197-2_19
T. Merkle, I. T. Holder, and J. S. Hartig
The dual aptamer approach: Rational design of a high-affinity FAD aptamer
Organic and Biomolecular Chemistry, 2016, 14, 447-450
doi: 10.1039/c5ob02026c
C. Rehm, L. A. Wurmthaler, Y. Li, T. Frickey, and J. S. Hartig
Investigation of a quadruplex-forming repeat sequence highly enriched in Xanthomonas and Nostoc sp.
PlosOne, 2015, 10, e0144275
doi: 10.1371/journal.pone.0144275
I. T. Holder, S. Wagner, P. Xiong, M. Sinn, T. Frickey, A. Meyer, and J. S. Hartig
Intrastrand triplex DNA repeats in bacteria: a source of genomic instability
Nucleic Acids Research, 2015, 43, 10126-10142
doi: 10.1093/nar/gkv1017
T. Merkle, M. Sinn, and J. S. Hartig
Interactions between Flavins and Quadruplex Nucleic Acids
ChemBioChem, 2015, 16(17), 2437-2440
doi: 10.1002/cbic.201500463
F. Wojciechowski, A. Groß, I. T. Holder, L. Knörr, M. Drescher, and J. S. Hartig
Pulsed EPR spectroscopy distance measurements of DNA internally labelled with Gd3+-DOTA
Chemical Communications, 2015, 51, 13850-13853
doi: 10.1039/C5CC04234H
B. Strobel, B. Klauser, J. S. Hartig, T. Lamla, and F. Gantner, F. Kreutz
Riboswitch-mediated attenuation of transgene cytotoxicity increases Adeno-associated virus vector yields in HEK-293 cells
Molecular Therapy, 2015, 23(10), 1582-1591
doi: 10.1038/mt.2015.123
B. Klauser, C. Rehm, D. Summerer, J. S. Hartig
Engineering of ribozyme-based aminoglycoside switches of gene expression by in vivo genetic selection in Saccharomyces cerevisiae
Methods in Enzymology, 2015, 550, 301-320
doi: 10.1016/bs.mie.2014.10.037
C. Rehm, B. Klauser, J. S. Hartig
Screening of genetic aptazyme switches for conditional gene expression using a mammalian cellular system
Methods in Molecular Biology, 2015, 1316, 127
S. Ausländer , P. Stücheli , C. Rehm , D. Ausländer , J. S. Hartig, M. Fussenegger
A general design strategy for protein-responsive riboswitches in mammalian cells
Nature Methods, 2014, 11, 1154-1160
doi: 10.1038/nmeth.3136
I. Holder, J. S. Hartig,
A matter of location: Positional effects of G-quadruplexes on Escherichia coli gene expression
Chemistry & Biology, 2014, 21, 1511-1521
doi: 10.1016/j.chembiol.2014.09.014
B. Klauser, J. Atanasov, L. Siewert, J.S. Hartig,
Ribozyme-based aminoglycoside switches of gene expression engineered by genetic selection in S. cerevisiae
ACS Synthetic Biology, 2014, 4, 516-525
doi: 10.1021/sb500062p
C. Rehm, I. T. Holder, A. Gross, F. Wojciechowski, M. Urban, M. Sinn, M. Drescher, J. S. Hartig
A bacterial DNA quadruplex with exceptional K+ selectivity and unique structural polymorphism
Chemical Science, 2014, 5, 2809-2818
doi: 10.1039/C4SC00440J
C. Rehm, J. S. Hartig
In vivo screening for aptazyme-based bacterial riboswitches
Methods in Molecular Biology, 2014, 1111, 237-249
doi: 10.1007/978-1-62703-755-6_17
P. Ketzer, J. K. Kaufmann, S. Engelhardt, S. Bossow, C. von Kalle, J. S. Hartig, G. Ungerechts, D. M. Nettelbeck
Artificial riboswitches for gene expression and replication control of DNA and RNA viruses
Proceedings of the National Academy of Sciences, 2014, 111, E554-E562
doi: 10.1073/pnas.1318563111
J. S. Hartig
Binding versus Triggering Riboswitches (commentary)
Chemistry and Biology, 2014, 21, 167
doi: 10.1016/j.chembiol.2014.02.002
A. Saragliadis, J. S. Hartig
Ribozyme-based tRNA switches for post-transcriptional control of amino acid identity in protein synthesis
Journal of the American Chemical Society, 2013, 135, 8222-8226
doi: 10.1021/ja311107p
A. Saragliadis, S. S. Krajewski, C. Rehm, F. Narberhaus, J. S. Hartig
Thermozymes: Synthetic RNA thermometers based on ribozyme activity
RNA Biology, 2013, 10, 1009-1016
doi: 10.4161/rna.24482
B. Klauser, J. S. Hartig
An engineered small RNA-mediated genetic switch based on a ribozyme expression platform
Nucleic Acids Research, 2013, 41, 5542-5552
doi: 10.1093%2Fnar%2Fgkt253
I. T. Holder, M. Drescher, J. S. Hartig,
Structural Characterization of Quadruplex DNA with in-cell EPR approaches
Bioorganic & Medicinal Chemistry, 2013, 21, 6156.6161
doi: 10.1016/j.bmc.2013.04.014
M. Azarkh, V. Singh, O. Okle, I. T. Seemann, D. Dietrich, J. S. Hartig, M. Drescher
Site directed spin labeling of nucleotides and the use of in-cell DEER: An EPR method for determination of long-range distances in cellulo
Nature Protocols, 2013, 8, 131
P. Ketzer, S. F. Haas, S. Engelhardt, J. S. Hartig, D. Nettelbeck
Synthetic riboswitches for external regulation of genes transferred by replication-deficient and oncolytic adenoviruses
Nucleic Acids Research, 2012, 40, e167
doi: 10.1093/nar/gks734
B. Klauser, A. Saragliadis, S. Ausländer, M. Wieland, M. R. Berthold, J. S. Hartig
Post-transcriptional Boolean computation by combining aptazymes controlling mRNA translation initiation and tRNA activation
Molecular Biosystems, 2012, 8, 2242-8
doi: 10.1039/c2mb25091h
L. Giacani, S. Brandt, M. Puray-Chavez, T. Brinck Reid, C. Godornes, B. Molini, M. Benzler, J. S. Hartig, S. Lukehart, A. Centurion-Lara
Comparative Investigation of the Genomic Regions Involved in Antigenic Variation of the TprK Antigen among Treponemal Species, Subspecies, and Strains
Journal of Bacteriology, 2012, 194, 4208-25
doi: 10.1128/JB.00863-12
V. Singh, M. Azarkh, M. Drescher, J. S. Hartig
Conformations of Individual Quadruplex Units studied in the Context of Extended Human Telomeric DNA
Chemical Communications, 2012, 48, 8258-60
doi: 10.1039/c2cc32012f
R. Halder, J.-F. Riou, M.-P. Teulade-Fichou, T. Frickey, J. S. Hartig
Bisquinolinium Compounds induce Quadruplex-Specific Transcriptome Changes in HeLa S3 Cell Lines
BMC Research Notes, 2012, 13, 138
doi: 10.1186/1756-0500-5-138
K. Halder, M. Benzler, J. S. Hartig,
Reporter assays for studying quadruplex nucleic acids
Methods, 2012, 57, 115-121
doi: 10.1016/j.ymeth.2012.02.005
M. Azarkh, V. Singh, O. Okle, D. R. Dietrich, J. S. Hartig,* M. Drescher*
Intracellular Conformations of Human Telomeric Quadruplexes Studied by EPR
ChemPhysChem, 2012, 13, 1444-1447
doi: 10.1002/cphc.201100980
A. Saragliadis, B. Klauser, J. S. Hartig,
In vivo screening of ligand-dependent hammerhead ribozymes
Methods in Molecular Biology, 2012, 848, 455-63
doi: 10.1007/978-1-61779-545-9_28
V. Singh, A. Benz, J. S. Hartig:
G-quadruplexes stabilized by 8-oxo-2´-deoxyguanosine
Chemistry - A European Journal, 2011, 17, 10838-10843
doi: 10.1002/chem.201100284
K. Halder, E. Largy, M. Benzler, M.-P. Teulade-Fichou, J. S. Hartig:
Efficient Suppression of Gene Expression by targeting 5'-UTR-based RNA Quadruplexes with Bisquinolinium Compounds
ChemBioChem, 2011, 12, 1663-1668
doi: 10.1002/cbic.201100228
M. Azarkh, O. Okle, I. Seemann, V. Singh, I. Seemann, J. S. Hartig, D. R. Dietrich, M. Drescher
Long-Range Distance Determination in a DNA Model System inside Xenopus Laevis Oocytes by In-Cell Spin-Label EPR
ChemBioChem, 2011, 12, 1992-1995
doi: 10.1002/cbic.201100281
A. Benz, V. Singh, T. U. Mayer, J. S. Hartig:
Identification of quadruplex ligands from small molecule libraries by FRET-based high-throughput screening
ChemBioChem, 2011, 12, 1422-1426
doi: 10.1002/cbic.201100094
I. T. Seemann, J. S. Hartig:
Artificial Ribozyme-Based Regulators of Gene Expression (Account)
Synlett, 2011, 11, 1486-1494
doi: 10.1055/s-0030-1260583
I. T. Seemann, V. Singh, M. Azarkh, M. Drescher, J. S. Hartig:
Small molecule-triggered manipulation of DNA three-way-junctions
Journal of the American Chemical Society, 2011, 133, 4706-4709
doi: 10.1021/ja110986u
J. S. Hartig:
A Group I Intron Riboswitch (Commentary)
Chemistry & Biology, 2010, 17, 920-1
doi: 10.1016/j.chembiol.2010.09.001
K. Halder, J. S. Hartig:
RNA Quadruplexes
(Structural and Catalytic Roles of Metal Ions in RNA)
Met Ions Life Science, 2011,9,125-39
doi: 10.1039/9781849732512-00125
M. Wieland, B. Berschneider, M. D. Erlacher, J. S. Hartig:
Aptazyme-mediated regulation of 16S ribosomal RNA
Chemistry & Biology, 2010, 17, 236-242
doi: 10.1016/j.chembiol.2010.02.012
J. S. Hartig:
Turning Riboswitches Loose (Highlight)
ChemBioChem, 2010, 11, 640-641
doi: 10.1002/cbic.201000045
S. Ausländer, P. Ketzer, J. S. Hartig:
A ligand-dependent hammerhead ribozyme switch for controlling mammalian gene expression
Molecular Biosystems, 2010, 6, 807-814
doi: 10.1039/B923076A
M. Wieland, A. Benz, J. Haar, K. Halder, J. S. Hartig:
Small molecule-triggered assembly of DNA nanoarchitectures
Chemical Communications, 2010, 46, 1866-1868
doi: 10.1039/B921481J
V. Singh, M. Azarkh, T. E. Exner, J. S. Hartig*, Malte Drescher:
Human Telomeric Quadruplex Conformations studied by pulsed EPR
Angewandte Chemie International Edition, 2009, 48, 9728-9730
doi; 10.1002/anie.200902146
A. Joachimi, A. Benz, J. S. Hartig:
A comparison of DNA and RNA quadruplex structures and stabilities
Bioorganic & Medicinal Chemistry, 2009, 17, 6811-6815
doi: 10.1016/j.bmc.2009.08.043
K. Halder, M. Wieland, J. S. Hartig:
Predictable suppression of gene expression by 5´-UTR-based RNA quadruplexes
Nucleic Acids Research, 2009, 37, 6811-7
doi: 10.1093/nar/gkp696
B. Berschneider, M. Wieland, M. Rubini, J. S. Hartig:
Small Molecule-dependent Regulation of transfer-RNA in a Bacterium
Angewandte Chemie International Edition, 2009, 48, 7564-7567
doi: 10.1002/anie.200900851
M. Wieland, J. S. Hartig:
Investigation of mRNA quadruplex formation in Escherichia coli
Nature Protocols, 2009, 4, 1632-1640
doi: 10.1038/nprot.2009.111
M. Wieland, M. Gfell, J. S. Hartig:
Expanded Hammerhead Ribozymes containing addressable Three-Way-Junctions
RNA, 2009, 15, 968-976
doi: 10.1261/rna.1220309
M. Wieland, A. Benz, B. Klauser, J. S. Hartig:
Artificial Ribozyme Switches containing natural Riboswitch Aptamer Domains
Angewandte Chemie International Edition, 2009, 48, 2715-2718
doi: 10.1002/anie.200805311
A. Henn, A. Joachimi, D. P. N. Gonçalves, D. Monchaud, M.-P. Teulade Fichou, J. K. M. Sanders, J. S. Hartig:
Inhibition of Dicing of Guanosine-rich shRNAs by Quadruplex-binding Compounds
ChemBioChem, 2008, 9, 2722-2729
doi: 10.1002/cbic.200800271
A. Benz, J. S. Hartig:
Redesigned Tetrads with altered Hydrogen Bonding Patterns enable Programming of Quadruplex Topologies
Chemical Communications, 2008, 34, 4010-4012
doi:10.1039/B805227A
M. Wieland, J. S. Hartig:
Artificial Riboswitches: Synthetic mRNA-based Regulators of Gene Expression
ChemBioChem, 2008, 9, 1873-1878
doi: 10.1002/cbic.200800154
Z. Tang, D. P. N. Goncalves, M. Wieland, A. Marx, J. S. Hartig:
Novel DNA Catalysts based on G-quadruplex Recognition
ChemBioChem, 2008, 9, 1061-1064
doi: 10.1002/cbic.200800024
M. Wieland, J. S. Hartig:
Improved Aptazyme Design and in vivo Screening enable Riboswitching in Bacteria
Angewandte Chemie International Edition, 2008, 47, 2604-2607
doi: 10.1002/anie.200703700
J. S. Hartig:
Teaching Bacteria new Tricks - with RNA Switches (Highlight)
Angewandte Chemie International Edition, 2007, 46, 7741-7743
doi: 10.1002/anie.200703088
V. Looser, S. M. Langenegger, R. Häner, J. S. Hartig:
Pyrene Modification Leads to Increased Catalytic Activity in Minimal Hammerhead Ribozymes
Chemical Communications, 2007, 42, 4357-9
doi: 10.1039/b711170c
M. Famulok, J. S. Hartig, G. Mayer
Functional Aptamers and Aptazymes in Biotechnology, Diagnostics, and Therapy
Chemical Reviews, 2007, 107, 3715-3743
doi.org/10.1021/cr0306743
M. Wieland, J. S. Hartig:
RNA quadruplex-based modulation of gene expression
Chemistry & Biology, 2007, 14, 757-763
doi: 10.1016/j.chembiol.2007.06.005
S. Yamazaki, L. Tan, G. Mayer, J. S. Hartig, J. N. Song, S. Reuter, T. Restle, S. D. Laufer, D. Grohman, H. G. Kräusslich, J. Bajorath, M. Famulok:
Aptamer displacement identifies alternative small molecule target sites that escape viral resistance
Chemistry & Biology, 2007, 14, 804-812
Doi: 10.1016/j.chembiol.2007.06.003
A. Joachimi, G. Mayer, J. S. Hartig:
A new anticoagulant-antidote pair: Control of thrombin activity by aptamers and porphyrins
Journal of the American Chemical Society, 2007, 129, 3036-3037
doi: 10.1021/ja0677822
J. S. Hartig, M. Famulok:
Screening of Molecular Interactions using Reporter Hammerhead Ribozymes, in: Molecular Beacons - signalling Nucleic Acid Probes
Methods in Molecular Biology, 2007
doi: 10.1007/978-1-60327-040-3_18
M. Wieland, J. S. Hartig:
Turning Inhibitors into Activators: A Guanine-Quadruplex-controlled Hammerhead Ribozyme
Angewandte Chemie International Edition, 2006, 45, 5875-5878
doi: 10.1002/anie.200600909
J. S. Hartig, E. T. Kool:
Efficient isothermal expansion of human telomeric and minisatellite repeats by Thermococcus litoralis DNA polymerase.
Nucleic Acids Research, 2005, 33(15), p4922-7
doi: 10.1093%2Fnar%2Fgki803
J. S. Hartig, S. Fernandez-Lopez, E. T. Kool:
Guanine-rich DNA nanocircles for the synthesis and characterization of long cytosine-rich telomeric DNAs.
ChemBioChem, 2005, 6(8), p1458-62
doi: 10.1002/cbic.200500015
J. S. Hartig
Protein-dependent ribozymes as reporters of protein-protein interactions, in: Protein - Protein Interactions, A Molecular Cloning Manual (2nd edition)
Cold Spring Harbor Laboratory Press, 2005, p549-60
J. S. Hartig, E. T. Kool:
Small circular DNAs for synthesis of the human telomere repeat: Varied sizes, structures and telomere-encoding activities.
Nucleic Acids Research, 2004 , 32(19), e152
doi: 10.1093/nar/gnh149
J. S. Hartig, I. Grüne, S. H. Najafi-Shoushtari, M. Famulok:
Sequence-specific Detection of microRNAs by Signal-amplifying Ribozymes
Journal of the American Chemical Society , 2004 , 126, p722-723
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Reporter ribozymes for domain-specific-real-time analysis of biomolecular interactions: HIV-1-reverse transcriptase and the primer-template complex
Angewandte Chemie International Edition, 2002, 41, p4263-4266
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J. S. Hartig, S. H. Najafi-Shoushtari, I. Grüne, A. Yan, A. D. Ellington, M. Famulok:
Protein-dependent ribozymes report molecular interactions in real time
Nature Biotechnology, 2002, 20, p717-722
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A. Jenne, J. S. Hartig, N. Piganeau, A. Tauer, D. A. Samarsky, M. R. Green, J. Davies, M. Famulok:
Rapid identification and characterization of hammerhead-ribozyme inhibitors using fluorescence-based technology
Nature Biotechnology, 2001, 19, p56-61
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